Symptoms may gradually worsen with age, although the decline may be somewhat faster for individuals who also suffer from an associated medical condition. Symptoms commonly occur in the late afternoon or evening hours, and are often most severe at night when a person is resting, such as Assumptions about restless leg syndrome or lying in bed. Other cases of RLS have no metart erotic hairy cause. Symptoms of restless legs syndrome Restless legs syndrome typically causes an overwhelming urge to move your legs and an uncomfortable sensation in your legs. People with RLS can sometimes experience remissions—spontaneous improvement over a period of weeks Assumptions about restless leg syndrome months before symptoms reappear—usually during the early stages of the disorder. Most people develop restless legs syndrome after age The mission of the National Institute of Neurological Disorders and Stroke NINDS is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.